MIT’s New AI, VaxSeer, Outperforms the WHO in Flu Vaccine Strain Selection

MIT’s CSAIL and Jameel Clinic have developed VaxSeer, an AI-powered system designed to predict which flu strains will dominate and how effectively vaccines will neutralize them—months ahead of time MIT News.

Why It Matters:

  • It uses deep learning models trained on decades of viral sequences and lab data to simulate the virus’s evolution and vaccine responses.
  • In a 10-year retrospective test, VaxSeer outperformed WHO vaccine strain selections for A/H3N2 in 9 out of 10 seasons, and matched or exceeded WHO choices for A/H1N1 in most seasons MIT News.
  • In some cases, like 2016, it identified strains a full year ahead of WHO corrections MIT News.

Takeaway Insight :
This is AI’s high-stakes debut in public health: anticipating viral threats before they’re visible, offering a blueprint for how AI can reshape vaccine development, global supply chains, and pandemic preparedness.

Imagine applying this to other fast-evolving threats—drug-resistant bacteria or cancer—prior to their emergence.